Effect of Virgin Olive Oil on the lipid profile of Hyperlipidemic induced Rats

Abstract

High olive oil content is associated with a significant reduction in incidence of heart diseases in comparison with normal fat diet. The aim of this study is to observe the effect of Virgin Olive Oil (VOO), low dose of virgin olive oil (LVOO)or high dose of virgin olive oil (HVOO) on the lipid profile of hyperlipidemic (HLD) rats.The results showed a significant decrease(P ≤ 0.05) in HDL-C, Triglycerides (TG), Total cholesterol(TC), low density lipoproteins (LDL-C) and very low density lipoproteins (VLDL-C) in rats supplemented with (LVOO) or (HVOO) as compared with both control (ND) and hyperlipidemic (HLD) groups, on other hand an increase (P ≤ 0.05) in high density Lipoprotein (HDLP) was recorded, as compared with that of both control (ND) and hyperlipidemic (HLD) groups. No significant difference between the LVOO and HVOO on the profile proteins,